EMD-53976
Rabbit 80S ribosome in complex with eRF1-AAQ, stalled at the Stop codon in mutated F2A sequence
EMD-53976
Single-particle2.65 Å
Deposition: 10/06/2025Map released: 21/01/2026
Last modified: 18/02/2026
Sample Organism:
Oryctolagus cuniculus,
Foot-and-mouth disease virus SAT 2,
Homo sapiens
Sample: Rabbit 80S ribosome stalled at the stop codon of a PGX mutant of the foot-and-mooth disease virus F2A sequence using dominant negative release factor eRF1-AAQ (human)
Fitted models: 9rhu
Deposition Authors: Li X
,
Zuber PK ,
Loughran G ,
Bhatt PR,
Alquraish F,
Ramakrishnan V,
Firth AE,
Atkins JF
Sample: Rabbit 80S ribosome stalled at the stop codon of a PGX mutant of the foot-and-mooth disease virus F2A sequence using dominant negative release factor eRF1-AAQ (human)
Fitted models: 9rhu
Deposition Authors: Li X
,
Zuber PK ,
Loughran G ,
Bhatt PR,
Alquraish F,
Ramakrishnan V,
Firth AE,
Atkins JF
Molecular architecture and diversity of StopGo/2A translational recoding.
Li X ,
Zuber PK ,
Loughran G ,
Bhatt PR,
Alquraish F,
Ramakrishnan V,
Firth AE,
Atkins JF
(2026) PNAS , 123 , e2528667123 - e2528667123
,
Zuber PK ,
Loughran G ,
Bhatt PR,
Alquraish F,
Ramakrishnan V,
Firth AE,
Atkins JF
(2026) PNAS , 123 , e2528667123 - e2528667123
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_U105184332 (United Kingdom)
- Wellcome Trust: WT096570 (United Kingdom)
- European Molecular Biology Organization (EMBO): ALTF 937-2022 (European Union)
- European Molecular Biology Organization (EMBO): ALTF 778-2021 (European Union)