EMD-53489

Single-particle
3.3 Å
EMD-53489
3D View Gallery
Deposition: 24/04/2025
Map released: 05/11/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53489
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9r10 summary report (pdf.gz) Map and 9r10 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human MATE1 in complex with cimetidine

EMD-53489

Single-particle
3.3 Å
EMD-53489
3D View Gallery
Deposition: 24/04/2025
Map released: 05/11/2025
Last modified: 05/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Human multidrug and toxin extrusion protein (MATE1) in complex with Fab and cimetidine
Fitted models: 9r10

Deposition Authors: Romane K , Peteani G, Mukherjee S , Kowal J , Rossi L , Hou J , Kossiakoff A, Lemmin T , Locher KP
Structural basis of drug recognition by human MATE1 transporter.
Romane K , Peteani G, Mukherjee S , Kowal J , Rossi L , Hou J , Kossiakoff AA , Lemmin T , Locher KP
(2025) Nat Commun , 16 , 9444 - 9444
PUBMED: 41145429
DOI: doi:10.1038/s41467-025-64490-z
ISSN: 2041-1723