EMD-53486

Single-particle
3.1 Å
EMD-53486
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Deposition: 24/04/2025
Map released: 11/02/2026
Last modified: 11/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53486
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9r0o summary report (pdf.gz) Map and 9r0o FULL report (pdf.gz)
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Cryo-EM structure of rat SLCO2A1 bound to tolcapone.

EMD-53486

Single-particle
3.1 Å
EMD-53486
3D View Gallery
Deposition: 24/04/2025
Map released: 11/02/2026
Last modified: 11/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus
Sample: SLCO2A1 protein in detergent-lipid micelle bound to tolcapone drug.
Fitted models: 9r0o

Deposition Authors: Deme JC, Joshi C, Lea SM, Newstead S

Structural basis for prostaglandin and drug transport via SLCO2A1.
Joshi C, Deme JC, Nakamura Y, Hsu W-T, Goult J, Kato T, Parker JL, Biggin PC, Lea SM, Nakanishi T, Newstead S
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