EMD-53392

Single-particle
7.0 Å
EMD-53392
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Deposition: 11/04/2025
Map released: 10/12/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53392
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human PAN2-PAN3 bound to a 90Ai/PABPC1 RNP

EMD-53392

Single-particle
7.0 Å
EMD-53392
3D View Gallery
Deposition: 11/04/2025
Map released: 10/12/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: heterotrimeric PAN2-PAN3 mRNA deadenylase complex composed of the regulatory PAN3 homodimer bound to the catalytic PAN2 in complex with an inhibitory 90Ai/PABPC1 RNP

Deposition Authors: Albrecht JC , Reitinger T , Basquin J , Schuessler S , Schaefer IB , Conti E
Mechanisms governing poly(A)-tail-length specificity of the human PAN2-PAN3 deadenylase complex.
Albrecht JC , Reitinger T , Basquin J , Schussler S, Riggi M, Schafer IB, Conti E
(2025) Cell Rep , 44 , 116609 - 116609
PUBMED: 41275497
DOI: doi:10.1016/j.celrep.2025.116609
ISSN: 2211-1247