EMD-53367

Single-particle
2.98 Å
EMD-53367
3D View Gallery
Deposition: 09/04/2025
Map released: 27/05/2026
Last modified: 17/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53367

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9qty summary report (pdf.gz) Map-9qty FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the binary MEGF8-MOSMO complex with nanobody 270

EMD-53367

Single-particle
2.98 Å
EMD-53367
3D View Gallery
Deposition: 09/04/2025
Map released: 27/05/2026
Last modified: 17/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Human MEGF8-MOSMO binary complex bound to nanobody 270
Fitted models: 9qty

Deposition Authors: Williams C, Carrique L, Pardon E, Nocka LM, Hedger G, Pusapati GV, Parashara P, Latorraca NR, Sarkar P, Lartey D, Gao L, Milenkovic L, Chalk R, Steyaert J, Bazan F, Rouse SL, Marqusee S, Kong JH, Rohatgi R, Siebold C
Design principles of a membrane-spanning ubiquitin ligase.
Williams C, Nocka LM, Hedger G, Parashara P, Pardon E, Latorraca NR, Pusapati GV, Sarkar P, Lartey D, Gao L, Milenkovic L, Chalk R, Steyaert J, Marqusee S, Carrique L, Bazan JF, Rouse SL, Kong JH, Siebold C, Rohatgi R
(2026) Mol Cell , 86 , 2207
PUBMED: 42190653
DOI: doi:10.1016/j.molcel.2026.05.001
ISSN: 1097-2765
ASTM: MOCEFL
Grant Support: