EMD-53248
Ternary complex of the human 20S proteasome in complex with Importin-9 and two homodimers of Akirin-2 - focussed refinement on Importin-9 and Akirin-2
EMD-53248
Single-particle4.2 Å
Deposition: 25/03/2025Map released: 28/01/2026
Last modified: 25/03/2026
Sample Organism:
Homo sapiens
Sample: Ternary complex of the human 20S proteasome in complex with two dimers of Akirin-2 and Importin-9
Fitted models: 9qno
Deposition Authors: Brunner HL
,
Grundmann L ,
David H
Sample: Ternary complex of the human 20S proteasome in complex with two dimers of Akirin-2 and Importin-9
Fitted models: 9qno
Deposition Authors: Brunner HL
,
Grundmann L ,
David H
A multivalent adaptor mechanism drives the nuclear import of proteasomes.
Brunner HL ,
Kalis RW ,
Grundmann L ,
Hodakova Z ,
Koskova Z ,
Grishkovskaya I ,
de Almeida M,
Hinterndorfer M ,
Knaudt H ,
Hofflin S,
Andersch F ,
Kotisch H,
Dickmanns A,
Cuylen-Haering S ,
Zuber J ,
Haselbach D
(2026) Nat Commun , 17
,
Kalis RW ,
Grundmann L ,
Hodakova Z ,
Koskova Z ,
Grishkovskaya I ,
de Almeida M,
Hinterndorfer M ,
Knaudt H ,
Hofflin S,
Andersch F ,
Kotisch H,
Dickmanns A,
Cuylen-Haering S ,
Zuber J ,
Haselbach D
(2026) Nat Commun , 17
Grant Support:
- H2020 Marie Curie Actions of the European Commission: 847548 (European Union)
- Austrian Science Fund: 10.55776/F79 (Austria)