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EMD-52571
Cryo-EM structure of mouse RNF213:UBE2L3 transthiolation intermediate, chemically stabilized, and ATPgS
EMD-52571
Single-particle3.8 Å
Deposition: 16/01/2025Map released: 10/12/2025
Last modified: 10/12/2025
Sample Organism:
Mus musculus,
Homo sapiens
Sample: Mouse RNF213:UBE2L3 transthiolation intermediate
Fitted models: 9i1j
Deposition Authors: Grabarczyk DB
,
Ahel J
,
Clausen T
Sample: Mouse RNF213:UBE2L3 transthiolation intermediate
Fitted models: 9i1j
Deposition Authors: Grabarczyk DB
,
Ahel J
,
Clausen T
ATP functions as a pathogen-associated molecular pattern to activate the E3 ubiquitin ligase RNF213.
Ahel J
,
Balci A
,
Faas V,
Grabarczyk DB
,
Harmo R
,
Squair DR,
Zhang J,
Roitinger E
,
Lamoliatte F,
Mathur S,
Deszcz L,
Bell LE
,
Lehner A,
Williams TL,
Sowar H,
Meinhart A,
Wood NT
,
Clausen T
,
Virdee S
,
Fletcher AJ
(2025) Nat Commun , 16 , 4414 - 4414
,
Balci A
,
Faas V,
Grabarczyk DB
,
Harmo R
,
Squair DR,
Zhang J,
Roitinger E
,
Lamoliatte F,
Mathur S,
Deszcz L,
Bell LE
,
Lehner A,
Williams TL,
Sowar H,
Meinhart A,
Wood NT
,
Clausen T
,
Virdee S
,
Fletcher AJ
(2025) Nat Commun , 16 , 4414 - 4414
Grant Support:
- Austrian Research Promotion Agency: 852936 (Austria)
