EMD-52445

Single-particle
3.5 Å
EMD-52445
3D View Gallery
Deposition: 02/01/2025
Map released: 14/01/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52445

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9hvy summary report (pdf.gz) Map-9hvy FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human separase-SCC1 (1-631) fusion protein

EMD-52445

Single-particle
3.5 Å
EMD-52445
3D View Gallery
Deposition: 02/01/2025
Map released: 14/01/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Separase-SCC1 fusion protein
Fitted models: 9hvy

Deposition Authors: Yu J , Schmidt S , Botto M , Boland A
Substrate recognition by human separase.
Yu J , Schmidt S , Botto M , Lee K, Ghent CM, Goodfried JM, Howe A, O'Reilly FJ, Morgan DO , Boland A
(2025) Sci Adv , 11 , eady9807 - eady9807
PUBMED: 41223273
DOI: doi:10.1126/sciadv.ady9807
ISSN: 2375-2548