EMD-52193
Co-chaperone Bag1-bound human 26S proteasome in SBAG2 state
EMD-52193
Single-particle3.5 Å
Deposition: 27/11/2024Map released: 31/12/2025
Last modified: 04/03/2026
Sample Organism:
Homo sapiens
Sample: Co-chaperone Bag1-bound human 26S proteasome in SBAG2 state
Fitted models: 9szt
Deposition Authors: Cheng TC
,
Sakata E ,
Muntaner J,
Maestro-Lopez M,
Cuellar J ,
Valpuesta JM
Sample: Co-chaperone Bag1-bound human 26S proteasome in SBAG2 state
Fitted models: 9szt
Deposition Authors: Cheng TC
,
Sakata E ,
Muntaner J,
Maestro-Lopez M,
Cuellar J ,
Valpuesta JM
Structures of the 26 S proteasome in complex with the Hsp70 co-chaperone Bag1 reveal a mechanism for direct substrate transfer.
Maestro-Lopez M,
Cheng TC ,
Muntaner J,
Menendez M ,
Alonso M,
Schweitzer A,
Ishizaka M ,
Tomko Jr RJ ,
Cuellar J ,
Valpuesta JM ,
Sakata E
(2026) Sci Adv , 12 , eadz3026 - eadz3026
,
Muntaner J,
Menendez M ,
Alonso M,
Schweitzer A,
Ishizaka M ,
Tomko Jr RJ ,
Cuellar J ,
Valpuesta JM ,
Sakata E
(2026) Sci Adv , 12 , eadz3026 - eadz3026
Grant Support:
- German Research Foundation (DFG): 154113120 (Germany)
- German Research Foundation (DFG): EXC 2067/1-390729940 (Germany)
- German Research Foundation (DFG): 448415290 (Germany)
- Spanish Ministry of Science, Innovation, and Universities: PID2022-137175NB-I00 (Spain)
- Spanish Ministry of Science, Innovation, and Universities: AEI/10.13039/501100011033 (Spain)
- Spanish Ministry of Science, Innovation, and Universities: CEX2023-001386-S (Spain)