EMD-51276
Cryo-EM structure of Vibrio cholerae RNA polymerase Transcription Activation Complex with TcpP transcription factor and a toxT promoter DNA fragment
EMD-51276
Composite mapSingle-particle
2.7 Å
Deposition: 06/08/2024Map released: 17/12/2025
Last modified: 28/01/2026
Sample Organism:
Vibrio cholerae O395
Sample: Virulent transcription complex #4
Fitted models: 9gdr
Deposition Authors: Alcaide-Jimenez A
,
Baudin F
,
Canals A
,
Machon C
,
Murciano B
,
Fabrega-Ferrer M
,
Bantysh O
,
Perez-Luque R,
Krukonis ES
,
Muller CW
,
Coll M
Sample: Virulent transcription complex #4
Fitted models: 9gdr
Deposition Authors: Alcaide-Jimenez A
,
Baudin F
,
Canals A
,
Machon C
,
Murciano B
,
Fabrega-Ferrer M
,
Bantysh O
,
Perez-Luque R,
Krukonis ES
,
Muller CW
,
Coll M
Structures of Vibrio cholerae transcription complexes reveal how ToxR and TcpP recruit the RNA polymerase and activate virulence genes.
Alcaide-Jimenez A
,
Canals A
,
Baudin F
,
Machon C
,
Fabrega-Ferrer M
,
Bantysh O
,
Perez-Luque R,
Murciano B
,
Mohammad AA,
Rowse MJ,
Ferracciolo JM,
Krukonis ES
,
Muller CW
,
Coll M
(2026) Sci Adv , 12 , eadx9680 - eadx9680
,
Canals A
,
Baudin F
,
Machon C
,
Fabrega-Ferrer M
,
Bantysh O
,
Perez-Luque R,
Murciano B
,
Mohammad AA,
Rowse MJ,
Ferracciolo JM,
Krukonis ES
,
Muller CW
,
Coll M
(2026) Sci Adv , 12 , eadx9680 - eadx9680
Grant Support:
