EMD-51249
DNA-PK Ku80 mediated dimer bound to DNA polymerase Lambda and DNA ligase 4/XRCC4
EMD-51249
Single-particle4.25 Å
Deposition: 05/08/2024Map released: 13/08/2025
Last modified: 18/02/2026
Sample Organism:
Homo sapiens
Sample: Ku80 mediated dimer of DNA-PK bound to Polymerase Lambda and XRCC4/DNA ligase IV
Fitted models: 9gd7
Deposition Authors: Chaplin AK
,
Amin H,
Zahid S ,
Hardwick SW
Sample: Ku80 mediated dimer of DNA-PK bound to Polymerase Lambda and XRCC4/DNA ligase IV
Fitted models: 9gd7
Deposition Authors: Chaplin AK
,
Amin H,
Zahid S ,
Hardwick SW
Structural and functional insights into the interaction between Ku70/80 and Pol X family polymerases in NHEJ.
Frit P ,
Amin H,
Zahid S ,
Barboule N,
Hall C,
Matharu G ,
Hardwick SW ,
Chauvat J ,
Britton S ,
Chirgadze DY ,
Ropars V,
Charbonnier JB ,
Calsou P ,
Chaplin AK
(2025) Nat Commun , 16 , 4208 - 4208
,
Amin H,
Zahid S ,
Barboule N,
Hall C,
Matharu G ,
Hardwick SW ,
Chauvat J ,
Britton S ,
Chirgadze DY ,
Ropars V,
Charbonnier JB ,
Calsou P ,
Chaplin AK
(2025) Nat Commun , 16 , 4208 - 4208
Grant Support:
- Medical Research Council (MRC, United Kingdom): MR/X00029X/1 (United Kingdom)
- The Lister Institute of Preventive Medicine: (United Kingdom)