EMD-51114

Composite map
Single-particle
2.87 Å
EMD-51114
3D View Gallery
Deposition: 19/07/2024
Map released: 04/06/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-51114
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9g77 summary report (pdf.gz) Map and 9g77 FULL report (pdf.gz)
EMICSS annotations (xml)

Mouse mitochondrial DNA polymerase gamma ternary complex in error-editing conformer

EMD-51114

Composite map
Single-particle
2.87 Å
EMD-51114
3D View Gallery
Deposition: 19/07/2024
Map released: 04/06/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, synthetic construct
Sample: Mouse mitochondrial DNA polymerase gamma ternary complex in error-editing conformer
Fitted models: 9g77

Deposition Authors: Valenzuela S , Falkenberg M
Modelling POLG mutations in mice unravels a critical role of POL gamma Beta in regulating phenotypic severity.
Corra S, Zuppardo A , Valenzuela S , Jenninger L, Cerutti R, Sillamaa S , Hoberg E, Johansson KAS , Rovsnik U, Volta S, Silva-Pinheiro P , Davis H, Trifunovic A , Minczuk M , Gustafsson CM , Suomalainen A , Zeviani M, Macao B , Zhu X , Falkenberg M , Viscomi C
(2025) Nat Commun , 16 , 4782 - 4782
PUBMED: 40404629
DOI: doi:10.1038/s41467-025-60059-y
ISSN: 2041-1723
Grant Support: