EMD-50890

Single-particle
3.12 Å
EMD-50890
3D View Gallery
Deposition: 03/07/2024
Map released: 21/05/2025
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50890

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of native SV2A in complex with TeNT-Hc, gangliosides and Pro-Macrobody 5, focused refinement on TeNT-Hc and gangliosides

EMD-50890

Single-particle
3.12 Å
EMD-50890
3D View Gallery
Deposition: 03/07/2024
Map released: 21/05/2025
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Ovis aries, Clostridium tetani E88, Lama glama
Sample: SV2A bound to TeNT-Hc, gangliosides and Pro-Macrobody 5

Deposition Authors: Schenck S , Brunner JD
Structures of native SV2A reveal the binding mode for tetanus neurotoxin and anti-epileptic racetams.
Schenck S , Laeremans T , Steyaert J , Brunner JD
(2025) Nat Commun , 16 , 4172 - 4172
PUBMED: 40325068
DOI: doi:10.1038/s41467-025-59545-0
ISSN: 2041-1723
Grant Support: