EMD-50890

Single-particle
3.12 Å
EMD-50890
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Deposition: 03/07/2024
Map released: 21/05/2025
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50890
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Cryo-EM structure of native SV2A in complex with TeNT-Hc, gangliosides and Pro-Macrobody 5, focused refinement on TeNT-Hc and gangliosides

EMD-50890

Single-particle
3.12 Å
EMD-50890
3D View Gallery
Deposition: 03/07/2024
Map released: 21/05/2025
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Ovis aries, Clostridium tetani E88, Lama glama
Sample: SV2A bound to TeNT-Hc, gangliosides and Pro-Macrobody 5

Deposition Authors: Schenck S , Brunner JD
Structures of native SV2A reveal the binding mode for tetanus neurotoxin and anti-epileptic racetams.
Schenck S , Laeremans T , Steyaert J , Brunner JD
(2025) Nat Commun , 16 , 4172 - 4172
PUBMED: 40325068
DOI: doi:10.1038/s41467-025-59545-0
ISSN: 2041-1723
Grant Support: