EMD-50519

Single-particle
4.1 Å
EMD-50519
3D View Gallery
Deposition: 02/06/2024
Map released: 12/03/2025
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50519
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9fk5 summary report (pdf.gz) Map and 9fk5 FULL report (pdf.gz)
EMICSS annotations (xml)

Zebrafish Betaglycan Orphan Domain (zfBGo) in complex with TGF-B3 and extracellular domains of TGFBRI and TGFBRII

EMD-50519

Single-particle
4.1 Å
EMD-50519
3D View Gallery
Deposition: 02/06/2024
Map released: 12/03/2025
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Danio rerio
Sample: Quinary complex of Zebrafish Betaglycan Orphan Domain (zfBGo) in complex with TGF-B3 and extracellular domains of TGFBRI and TGFBRII
Fitted models: 9fk5

Deposition Authors: Wieteska L , Coleman JA, Hinck AP
Structures of TGF-beta with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling.
Wieteska L , Taylor AB , Punch E, Coleman JA, Conway IO, Lin YF , Byeon CH , Hinck CS, Krzysiak T, Ishima R, Lopez-Casillas F , Cherepanov P , Bernard DJ , Hill CS , Hinck AP
(2025) Nat Commun , 16 , 1778 - 1778
PUBMED: 40011426
DOI: doi:10.1038/s41467-025-56796-9
ISSN: 2041-1723