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EMD-50306
Structure of Pol II-TC-NER-STK19 complex, focused on CSA-DDB1-DDA1-CSB
EMD-50306
Single-particle3.2 Å
Deposition: 15/05/2024Map released: 13/11/2024
Last modified: 08/01/2025
Sample Organism:
Homo sapiens
Sample: Ternary complex of Pol II-TC-NER-STK19, focused on CSA-DDB1-DDA1-CSB
Deposition Authors: Lee S-H
,
Sixma TK
Sample: Ternary complex of Pol II-TC-NER-STK19, focused on CSA-DDB1-DDA1-CSB
Deposition Authors: Lee S-H
,
Sixma TK
STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment.
Ramadhin AR ,
Lee SH,
Zhou D,
Salmazo A,
Gonzalo-Hansen C,
van Sluis M ,
Blom CMA,
Janssens RC,
Raams A,
Dekkers D,
Bezstarosti K,
Slade D ,
Vermeulen W,
Pines A,
Demmers JAA,
Bernecky C ,
Sixma TK ,
Marteijn JA
(2024) Mol Cell , 84 , 4740 - 4757.e12
,
Lee SH,
Zhou D,
Salmazo A,
Gonzalo-Hansen C,
van Sluis M ,
Blom CMA,
Janssens RC,
Raams A,
Dekkers D,
Bezstarosti K,
Slade D ,
Vermeulen W,
Pines A,
Demmers JAA,
Bernecky C ,
Sixma TK ,
Marteijn JA
(2024) Mol Cell , 84 , 4740 - 4757.e12
Grant Support:
- Netherlands Organisation for Scientific Research (NWO): TOP 714.017.003 (Netherlands)
- Oncode Institute: (Netherlands)