EMD-50226

Single-particle
3.9 Å
EMD-50226
3D View Gallery
Deposition: 01/05/2024
Map released: 07/08/2024
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50226

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9f6j summary report (pdf.gz) Map-9f6j FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human DNA Polymerase epsilon bound to T-C mismatched DNA (Polymerase Arrest state)

EMD-50226

Single-particle
3.9 Å
EMD-50226
3D View Gallery
Deposition: 01/05/2024
Map released: 07/08/2024
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Quaternary Complex of human leading strand polymerase epsilon, Proliferating cell nuclear antigen (PCNA), substrate DNA and incoming nucleotide.
Fitted models: 9f6j

Deposition Authors: Roske JJ , Yeeles JTP
Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Roske JJ , Yeeles JTP
(2024) Nat Struct Mol Biol , 31 , 1921 - 1931
PUBMED: 39112807
DOI: doi:10.1038/s41594-024-01370-y
ISSN: 1545-9985
Grant Support: