EMD-50224

Single-particle
3.75 Å
EMD-50224
3D View Gallery
Deposition: 01/05/2024
Map released: 07/08/2024
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50224

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9f6f summary report (pdf.gz) Map-9f6f FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human DNA polymerase epsilon bound to DNA and PCNA (closed conformation)

EMD-50224

Single-particle
3.75 Å
EMD-50224
3D View Gallery
Deposition: 01/05/2024
Map released: 07/08/2024
Last modified: 25/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Quaternary Complex of human leading strand polymerase epsilon, Proliferating cell nuclear antigen (PCNA), substrate DNA and incoming nucleotide.
Fitted models: 9f6f

Deposition Authors: Roske JJ , Yeeles JTP
Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon.
Roske JJ , Yeeles JTP
(2024) Nat Struct Mol Biol , 31 , 1921 - 1931
PUBMED: 39112807
DOI: doi:10.1038/s41594-024-01370-y
ISSN: 1545-9985
Grant Support: