EMD-50184

Single-particle
3.74 Å
EMD-50184
3D View Gallery
Deposition: 26/04/2024
Map released: 14/08/2024
Last modified: 28/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50184

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9f45 summary report (pdf.gz) Map-9f45 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

cryo-EM structure of human LST2 bound to human mTOR complex 1

EMD-50184

Single-particle
3.74 Å
EMD-50184
3D View Gallery
Deposition: 26/04/2024
Map released: 14/08/2024
Last modified: 28/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: mTORC1 in complex with LST2
Fitted models: 9f45

Deposition Authors: Craigie LM , Maier T
mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR.
Battaglioni S , Craigie LM , Filippini S , Maier T , Hall MN
(2024) PNAS , 121 , e2405959121 - e2405959121
PUBMED: 39141345
DOI: doi:10.1073/pnas.2405959121
ISSN: 1091-6490
ASTM: PNASA6