EMD-50035

Single-particle
3.3 Å
EMD-50035
3D View Gallery
Deposition: 05/04/2024
Map released: 22/01/2025
Last modified: 16/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-50035

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

SARS-CoV-2 M protein dimer (long form) in complex with Fab-E and incubated with CIM-834

EMD-50035

Single-particle
3.3 Å
EMD-50035
3D View Gallery
Deposition: 05/04/2024
Map released: 22/01/2025
Last modified: 16/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Mus musculus
Sample: SARS-CoV-2 M protein dimer (long form) in complex with Fab-E and incubated with CIM-834

Deposition Authors: Debski-Antoniak O , Hurdiss DL
A coronavirus assembly inhibitor that targets the viral membrane protein.
Laporte M , Jochmans D , Bardiot D, Desmarets L , Debski-Antoniak OJ, Mizzon G , Abdelnabi R , Leyssen P , Chiu W , Zhang Z, Nomura N , Boland S, Ohto U , Stahl Y , Wuyts J, De Jonghe S , Stevaert A , van Hemert MJ, Bontes BW , Wanningen P, Groenewold GJM , Zegar A , Owczarek K , Joshi S, Koukni M, Arzel P, Klaassen H, Vanherck JC, Vandecaetsbeek I, Cremers N , Donckers K, Francken T, Van Buyten T, Rymenants J , Schepers J, Pyrc K , Hilgenfeld R, Dubuisson J , Bosch BJ , Van Kuppeveld F, Eydoux C , Decroly E , Canard B, Naesens L , Weynand B , Snijder EJ , Belouzard S , Shimizu T , Bartenschlager R , Hurdiss DL , Marchand A, Chaltin P, Neyts J
(2025) Nature , 640 , 514 - 523
PUBMED: 40140569
DOI: doi:10.1038/s41586-025-08773-x
ISSN: 1476-4687
ASTM: NATUAS