EMD-49964
Global map of six VRC35 Fabs and three MEDI8852 Fabs bound to influenza H3N2 Victoria 2011 hemaglutinin
EMD-49964
Single-particle3.39 Å
Deposition: 01/04/2025Map released: 29/04/2026
Last modified: 09/09/2026
Sample Organism:
Homo sapiens
Sample: Cryo-EM structure of influenza H3N2 Victoria 2011 hemagglutinin bound with VRC35 Fab and MEDI8852 Fab
Deposition Authors: Cheng J
,
Cale EM,
Longo N,
Sutton MS ,
Lei H,
Huang R,
Morton AJ,
Lang ZC,
Morano NC,
Roark RS,
Becker JE,
Tsybovsky Y,
Li N,
Zhang B,
Du H,
Rubin S ,
Shapiro L ,
Pierson TC,
Doria-Rose NA ,
Kwong PD ,
Zhou T
Sample: Cryo-EM structure of influenza H3N2 Victoria 2011 hemagglutinin bound with VRC35 Fab and MEDI8852 Fab
Deposition Authors: Cheng J
,
Cale EM,
Longo N,
Sutton MS ,
Lei H,
Huang R,
Morton AJ,
Lang ZC,
Morano NC,
Roark RS,
Becker JE,
Tsybovsky Y,
Li N,
Zhang B,
Du H,
Rubin S ,
Shapiro L ,
Pierson TC,
Doria-Rose NA ,
Kwong PD ,
Zhou T
Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields.
Cheng J ,
Cale EM,
Maghsoudi A ,
Sutton MS ,
Longo NS ,
Gillespie RA,
Wang L,
Kosik I,
Chong S ,
Yasuhara A,
Bylund T,
Schon A ,
Tripathi P ,
Tsybovsky Y,
Lei H,
Morano NC,
Lupatkin AB ,
Morton AJ,
Lang ZC,
Becker JE,
Frascilla IR,
Lee M ,
Li N,
Liu C ,
Roark RS,
Shen CH,
Teng IT,
Van Wazer DJ ,
Wang D ,
Wu L ,
Ahlsen G,
Castro M,
Du H,
Ernandes MJ ,
Li T,
Lin BC,
Louder MK,
McKee K,
Merriam JS ,
O'Dell S,
Ou L ,
Pletnev S,
Prikryl D,
Qiu Q ,
Rubin S ,
Sastry M,
Schmidt SD,
Shajahan A,
Shiakolas AR ,
Srivatsan S ,
Zhang B,
Zhou Q,
Connors M ,
Gall JG ,
Guo Y ,
Huang RK,
Huang Y,
Koup RA,
Lei QP ,
Mascola JR,
Rawi R,
Serebryannyy L,
Shapiro L ,
Sheng Z ,
Ho DD,
Wilson PC,
Yewdell JW,
Pierson TC,
Kanekiyo M ,
Doria-Rose NA ,
Kwong PD ,
Zhou T
(2026) Adv Sci , e77172 - e77172
,
Cale EM,
Maghsoudi A ,
Sutton MS ,
Longo NS ,
Gillespie RA,
Wang L,
Kosik I,
Chong S ,
Yasuhara A,
Bylund T,
Schon A ,
Tripathi P ,
Tsybovsky Y,
Lei H,
Morano NC,
Lupatkin AB ,
Morton AJ,
Lang ZC,
Becker JE,
Frascilla IR,
Lee M ,
Li N,
Liu C ,
Roark RS,
Shen CH,
Teng IT,
Van Wazer DJ ,
Wang D ,
Wu L ,
Ahlsen G,
Castro M,
Du H,
Ernandes MJ ,
Li T,
Lin BC,
Louder MK,
McKee K,
Merriam JS ,
O'Dell S,
Ou L ,
Pletnev S,
Prikryl D,
Qiu Q ,
Rubin S ,
Sastry M,
Schmidt SD,
Shajahan A,
Shiakolas AR ,
Srivatsan S ,
Zhang B,
Zhou Q,
Connors M ,
Gall JG ,
Guo Y ,
Huang RK,
Huang Y,
Koup RA,
Lei QP ,
Mascola JR,
Rawi R,
Serebryannyy L,
Shapiro L ,
Sheng Z ,
Ho DD,
Wilson PC,
Yewdell JW,
Pierson TC,
Kanekiyo M ,
Doria-Rose NA ,
Kwong PD ,
Zhou T
(2026) Adv Sci , e77172 - e77172
Grant Support: