EMD-49948

Single-particle
4.46 Å
EMD-49948
3D View Gallery
Deposition: 31/03/2025
Map released: 03/06/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49948
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9nz2 summary report (pdf.gz) Map and 9nz2 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of antibody 22F5 in complex with pre-fusion stabilized LayV-F

EMD-49948

Single-particle
4.46 Å
EMD-49948
3D View Gallery
Deposition: 31/03/2025
Map released: 03/06/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Langya virus
Sample: 22F5 Antibody Fab bound to pre-fusion stabilized Langya virus fusion protein
Fitted models: 9nz2

Deposition Authors: May AJ, Kumar U, Acharya P
Mechanistic and antigenic boundaries of Henipavirus and Parahenipavirus glycoproteins.
May AJ, Lella M, Lindenberger J, Berkman A, Kumar U, Liu K, Dutta M, Barr M, Parks R, Lu X, Berry M, Powell A, Thompson AG, Sowdamini Nakka S, Franca CT, Huang X, Mrigwani A, Song K, Ilevbare V, Sammour S, Park CS, Devkota Adhikari R, Devkota P, Janowska K, Liu Y, Scapellato G, Spence TN, Mansouri K, Wiehe K, Sullivan NJ, Mason R, Edwards RJ, Saunders KO, Haynes BF, Acharya P
(2026) Nat Commun
PUBMED: 42321170
DOI: doi:10.1038/s41467-026-74212-8
ISSN: 2041-1723