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EMD-49708

Single-particle
2.6 Å
EMD-49708
3D View Gallery
Deposition: 13/03/2025
Map released: 12/11/2025
Last modified: 31/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49708
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9nqz summary report (pdf.gz) Map and 9nqz FULL report (pdf.gz)
EMICSS annotations (xml)

cryo-EM structure of broad betacoronavirus binding antibody 1871 in complex with OC43 S2 subunit

EMD-49708

Single-particle
2.6 Å
EMD-49708
3D View Gallery
Deposition: 13/03/2025
Map released: 12/11/2025
Last modified: 31/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Human coronavirus OC43
Sample: OC43 S2 subunit complex with Fab 1871
Fitted models: 9nqz

Deposition Authors: Muthuraman K, Jackman MJ, Julien JP
Human antibody targeting of coronavirus spike S2 subunit is associated with protection mediated by Fc effector functions.
Muthuraman K, Jackman M, Liang Y, Garrett ME, Cui H, Nguyen LVH, Ivanochko D, Ye C, Pino PA, Hicks A, Maingot B, Yusko E, Benzeno S, Martinez-Sobrido L, Torrelles JB, Gilbert AE, Rubin BER, Keitany G, Jetha A, Julien J-P
(2025) J Virol , 99 , e0152325 - e0152325
PUBMED: 41222229
DOI: doi:10.1128/jvi.01523-25
ISSN: 1098-5514
ASTM: JOVIAM
Grant Support: