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EMD-49646

Single-particle
2.97 Å
EMD-49646
3D View Gallery
Deposition: 12/03/2025
Map released: 19/11/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49646
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9nq9 summary report (pdf.gz) Map and 9nq9 FULL report (pdf.gz)
EMICSS annotations (xml)

Magnesium ions-bound closed-state cryo-EM structure of human TRPV6 in cNW11 nanodiscs

EMD-49646

Single-particle
2.97 Å
EMD-49646
3D View Gallery
Deposition: 12/03/2025
Map released: 19/11/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: sample 1
Fitted models: 9nq9

Deposition Authors: Neuberger A , Sobolevsky AI
The locking mechanism of human TRPV6 inhibition by intracellular magnesium.
Neuberger A , Shalygin A, Veretenenko II , Trofimov YA , Gudermann T , Chubanov V , Efremov RG , Sobolevsky AI
(2025) Nat Commun , 16 , 9826 - 9826
PUBMED: 41198662
DOI: doi:10.1038/s41467-025-65919-1
ISSN: 2041-1723