EMD-49626

Single-particle
3.4 Å
EMD-49626
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Deposition: 11/03/2025
Map released: 19/03/2025
Last modified: 01/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49626
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Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9np6 summary report (pdf.gz) Map and 9np6 FULL report (pdf.gz)
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Cryo-EM structure of AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP and blunt end DNA

EMD-49626

Single-particle
3.4 Å
EMD-49626
3D View Gallery
Deposition: 11/03/2025
Map released: 19/03/2025
Last modified: 01/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mycolicibacterium smegmatis MC2 155, Mycolicibacterium smegmatis, synthetic construct
Sample: AdnA(D934A)-AdnB(D1014A) in complex with AMPPNP and blunt end DNA
Fitted models: 9np6

Deposition Authors: Warren GM , De la Cruz MJ, Goldgur Y, Shuman S
Structure of an initiation complex of mycobacterial helicase-nuclease AdnAB at a blunt double-strand break reveals local melting that engages the 3' tracking strand at the ratchet pawl of the helicase motor.
Warren GM , Jason de la Cruz M, Goldgur Y, Shuman S
(2026) Nucleic Acids Res , 54
PUBMED: 41854076
DOI: doi:10.1093/nar/gkag243
ISSN: 1362-4962
ASTM: NARHAD