EMD-49538

Composite map
Single-particle
2.91 Å
EMD-49538
3D View Gallery
Deposition: 04/03/2025
Map released: 08/10/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49538
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9nmr summary report (pdf.gz) Map and 9nmr FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of mouse RyR1 (including auxiliary transmembrane helix TMx; EGTA-only dataset)

EMD-49538

Composite map
Single-particle
2.91 Å
EMD-49538
3D View Gallery
Deposition: 04/03/2025
Map released: 08/10/2025
Last modified: 24/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Complex of RyR1 with Calstabin-1 (EGTA condition)
Fitted models: 9nmr

Deposition Authors: Weninger G, Marks AR
Structural basis for simvastatin-induced skeletal muscle weakness associated with type 1 ryanodine receptor T4709M mutation.
Weninger G, Dridi H, Reiken S, Yuan Q, Zhao N, Groom L, Leigh J, Liu Y, Tchagou C, Kang J, Chang A, Luna-Figueroa E, Miotto MC, Wronska A, Dirksen RT, Marks AR
(2025) J Clin Inv , 135
PUBMED: 41392983
DOI: doi:10.1172/JCI194490
ISSN: 0021-9738
ASTM: JCINAO