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EMD-49405

Single-particle
3.02 Å
EMD-49405
3D View Gallery
Deposition: 24/02/2025
Map released: 12/11/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49405
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9nh7 summary report (pdf.gz) Map and 9nh7 FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM Structure of De Novo VHH, VHH_flu_01, bound to influenza HA, strain A/USA:Iowa/1943 H1N1

EMD-49405

Single-particle
3.02 Å
EMD-49405
3D View Gallery
Deposition: 24/02/2025
Map released: 12/11/2025
Last modified: 19/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct, Influenza A virus (strain A/USA:Iowa/1943 H1N1)
Sample: De Novo VHH, VHH_flu_01, bound to influenza HA, strain A/USA:Iowa/1943 H1N1.
Fitted models: 9nh7

Deposition Authors: Borst AJ, Weidle C
Atomically accurate de novo design of antibodies with RFdiffusion.
Bennett NR, Watson JL, Ragotte RJ, Borst AJ, See DL, Weidle C, Biswas R, Yu Y, Shrock EL, Ault R, Leung PJY, Huang B, Goreshnik I, Tam J, Carr KD, Singer B, Criswell C, Wicky BIM, Vafeados D, Garcia Sanchez M, Kim HM, Vazquez Torres S, Chan S, Sun SM, Spear TT, Sun Y, O'Reilly K, Maris JM, Sgourakis NG, Melnyk RA, Liu CC, Baker D
(2025) Nature
PUBMED: 41193805
DOI: doi:10.1038/s41586-025-09721-5
ISSN: 1476-4687
ASTM: NATUAS