EMD-49207

Single-particle
3.19 Å
EMD-49207
3D View Gallery
Deposition: 13/02/2025
Map released: 25/02/2026
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49207
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9nb3 summary report (pdf.gz) Map and 9nb3 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of quaternary complex of human phosphoribosylglycinamidine synthase with thioester intermediate bound (at glutaminase site) and AMPPNP and FGAR (at synthase site).

EMD-49207

Single-particle
3.19 Å
EMD-49207
3D View Gallery
Deposition: 13/02/2025
Map released: 25/02/2026
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM structure of quaternary complex of human phosphoribosylglycinamidine synthase with thioester intermediate bound (at glutaminase site) and AMPPNP and FGAR (at synthase site)
Fitted models: 9nb3

Deposition Authors: Sharma N, French JB
Structural and molecular basis for allosteric regulation and catalytic coupling of human phosphoribosylformylglycinamidine synthase
Sharma N, Zhou W, French JB
(2026) Nat Commun
DOI: doi:10.1038/s41467-026-69423-y
ISSN: 2041-1723