EMD-49206

Single-particle
3.85 Å
EMD-49206
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Deposition: 13/02/2025
Map released: 21/01/2026
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49206
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Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
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CRYO-EM STRUCTURE OF human U7 SNRNP WITH MUTANT LSM11 that disrupts contacts with CPSF73

EMD-49206

Single-particle
3.85 Å
EMD-49206
3D View Gallery
Deposition: 13/02/2025
Map released: 21/01/2026
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Trichoplusia ni, Mus musculus
Sample: Full U7 snRNP complex assembled with LSm11 helix mutant
Fitted models: 9nb1

Deposition Authors: Desotell A, Tong L
An N-terminal helix of Lsm11 stabilizes CPSF73 in U7 snRNP for histone pre-mRNA 3'-end processing.
Desotell A, Marzluff WF, Dominski Z, Tong L
(2026) Nucleic Acids Res , 54
PUBMED: 41495886
DOI: doi:10.1093/nar/gkaf1442
ISSN: 1362-4962
ASTM: NARHAD