EMD-49198

Single-particle
3.22 Å
EMD-49198 Deposition: 12/02/2025
Map released: 25/02/2026
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49198

Cryo-EM structure of ternary complex of human phosphoribosylglycinamidine synthase with the intermediate (iminophosphate) and ADP bound at the synthase site.

EMD-49198

Single-particle
3.22 Å
EMD-49198 Deposition: 12/02/2025
Map released: 25/02/2026
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human phosphoribosylglycinamidine synthase
Fitted models: 9nal

Deposition Authors: Sharma N, French JB
Structural and molecular basis for allosteric regulation and catalytic coupling of human phosphoribosylformylglycinamidine synthase
Sharma N, Zhou W, French JB
(2026) Nat Commun
DOI: doi:10.1038/s41467-026-69423-y
ISSN: 2041-1723