EMD-49184

Single-particle
2.54 Å
EMD-49184
3D View Gallery
Deposition: 11/02/2025
Map released: 23/07/2025
Last modified: 22/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49184

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9nab summary report (pdf.gz) Map-9nab FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the alpha5beta1 integrin headpiece with OS2966 Fab

EMD-49184

Single-particle
2.54 Å
EMD-49184
3D View Gallery
Deposition: 11/02/2025
Map released: 23/07/2025
Last modified: 22/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Human integrin alpha5beta1 headpiece in complex with the Fab fragment of OS2966
Fitted models: 9nab

Deposition Authors: Wang L, Zhang C
ITGB1 Regulates Triple-Negative Breast Cancer Development by Modulating the Tumor Microenvironment.
Song N , Chen S, Wang L, Dang J, Cao X, Singh S, Yang L, Wang J, Rosen ST, Wang Y, Chen CD, Zhang C, Feng M
(2026) Adv Sci , 13 , e13672 - e13672
PUBMED: 41632816
DOI: doi:10.1002/advs.202513672
ISSN: 2198-3844