EMD-49179

Single-particle
3.31 Å
EMD-49179
3D View Gallery
Deposition: 11/02/2025
Map released: 25/02/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49179

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9n9w summary report (pdf.gz) Map-9n9w FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of AMPPNP bound human phosphoribosylformylglycinamidine synthase

EMD-49179

Single-particle
3.31 Å
EMD-49179
3D View Gallery
Deposition: 11/02/2025
Map released: 25/02/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: AMPPNP bound human phosphoribosylformylglycinamidine synthase
Fitted models: 9n9w

Deposition Authors: Sharma N , French JB
Structural and molecular basis for allosteric regulation and catalytic coupling of human phosphoribosylformylglycinamidine synthase.
Sharma N , Zhou W, French JB
(2026) Nat Commun , 17
PUBMED: 41688441
DOI: doi:10.1038/s41467-026-69423-y
ISSN: 2041-1723