EMD-49158

Single-particle
2.95 Å
EMD-49158
3D View Gallery
Deposition: 10/02/2025
Map released: 11/06/2025
Last modified: 20/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49158

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9n93 summary report (pdf.gz) Map-9n93 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human TMEM63A mutant V53M lipid-open state

EMD-49158

Single-particle
2.95 Å
EMD-49158
3D View Gallery
Deposition: 10/02/2025
Map released: 11/06/2025
Last modified: 20/08/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: TMEM63A V53M mutant
Fitted models: 9n93

Deposition Authors: Zheng W, Fu TM, Holt JR
Structural and functional basis of mechanosensitive TMEM63 channelopathies.
Zheng W, Lowry AJ, Smith HE , Xie J, Rawson S, Wang C , Ou J , Sotomayor M , Fu TM, Yang H, Holt JR
(2025) Neuron , 113 , 2474
PUBMED: 40480214
DOI: doi:10.1016/j.neuron.2025.05.009
ISSN: 0896-6273
ASTM: NERNET