EMD-49073
Consensus map for GluK2-2xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate
EMD-49073
Single-particle3.6 Å
Deposition: 05/02/2025Map released: 18/02/2026
Last modified: 02/09/2026
Sample Organism:
Rattus norvegicus
Sample: Consensus map for GluK2-2xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate
Deposition Authors: Gangwar SP
,
Yelshanskaya MV ,
Yen LY ,
Newton TP ,
Sobolevsky AI
Sample: Consensus map for GluK2-2xNeto2 in the open state, in complex with the positive allosteric modulator BPAM344 and agonist kainate
Deposition Authors: Gangwar SP
,
Yelshanskaya MV ,
Yen LY ,
Newton TP ,
Sobolevsky AI
Activation of kainate receptor GluK2-Neto2 complex.
Gangwar SP ,
Yelshanskaya MV ,
Yen LY ,
Newton TP ,
Sobolevsky AI
(2025) Nat Struct Mol Biol , 32 , 2176 - 2184
,
Yelshanskaya MV ,
Yen LY ,
Newton TP ,
Sobolevsky AI
(2025) Nat Struct Mol Biol , 32 , 2176 - 2184
Grant Support:
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): R01 NS083660 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): R01 NS107253 (United States)
- National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIH/NIAMS): R01 AR078814 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): R01 CA206573 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): R21 NS139087 (United States)