EMD-49059

Single-particle
3.6 Å
EMD-49059
3D View Gallery
Deposition: 05/02/2025
Map released: 10/12/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-49059

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9n6e summary report (pdf.gz) Map-9n6e FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

L9-targeting immunogen bound to three copies of L9 Fab

EMD-49059

Single-particle
3.6 Å
EMD-49059
3D View Gallery
Deposition: 05/02/2025
Map released: 10/12/2025
Last modified: 17/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Plasmodium falciparum
Sample: De novo immunogen bound to three copies of L9 Fab
Fitted models: 9n6e

Deposition Authors: Garfinkle SE , Lin ZJ, Pallesen J
Machine learning enables de novo multiepitope design of Plasmodium falciparum circumsporozoite protein to target trimeric L9 antibody.
Nelson JAD , Garfinkle SE , Lin ZJ, Park J, Kim AJ, Bayruns K, McCanna ME, Konrath KM, Agostino CJ , Kulp DW, Odom John AR , Pallesen J
(2025) PNAS , 122 , e2512358122 - e2512358122
PUBMED: 41337490
DOI: doi:10.1073/pnas.2512358122
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: