EMD-48828

Single-particle
3.0 Å
EMD-48828
3D View Gallery
Deposition: 28/01/2025
Map released: 15/07/2026
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48828

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Focused refinement map of hM4Di(GRANPA) in complex with mGsI and diphenhydramine

EMD-48828

Single-particle
3.0 Å
EMD-48828
3D View Gallery
Deposition: 28/01/2025
Map released: 15/07/2026
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human M4Di(GRANPA)-miniGsI-Gb1g2 complex

Deposition Authors: Mobbs JI , Thal DM
Next-generation chemogenetic inhibition using a brain-permeant non-prescription agent.
Devenish SO, Patel SD, Ussingkaer LV, Almeida Silva LF, Goff O, Richardson A, Mobbs JI , Venugopal H, Thal DM , Kullmann DM
(2026) Signal Transduct Target Ther , 11
PUBMED: 42393022
DOI: doi:10.1038/s41392-026-02865-4
ISSN: 2059-3635