EMD-48630

Single-particle
4.0 Å
EMD-48630
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Deposition: 13/01/2025
Map released: 16/04/2025
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48630
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Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
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Cryo-EM structure of CRISPR-associated cA4 bound Cat1 Pentagonal filament assembly in the presence of NAD (ADPR modelled)

EMD-48630

Single-particle
4.0 Å
EMD-48630
3D View Gallery
Deposition: 13/01/2025
Map released: 16/04/2025
Last modified: 25/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: bacterium
Sample: Antiviral protein Cat1 - Cyclic Tetra-Adenylate Complex NAD substrate was mixed with the sample.
Fitted models: 9mue

Deposition Authors: Majumder P , Patel DJ
Cat1 forms filament networks to degrade NAD + during the type III CRISPR-Cas antiviral response.
Baca CF , Majumder P , Hickling JH , Patel DJ , Marraffini LA
(2025) Science , 388 , eadv9045 - eadv9045
PUBMED: 40208959
DOI: doi:10.1126/science.adv9045
ISSN: 1095-9203
ASTM: SCIEAS