EMD-48627

Single-particle
2.5 Å
EMD-48627
3D View Gallery
Deposition: 13/01/2025
Map released: 03/12/2025
Last modified: 03/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48627
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9mub summary report (pdf.gz) Map and 9mub FULL report (pdf.gz)
EMICSS annotations (xml)

Human IMPDH2 mutant - S160del, treated with GTP, ATP, IMP, and NAD+; tetramer reconstruction

EMD-48627

Single-particle
2.5 Å
EMD-48627
3D View Gallery
Deposition: 13/01/2025
Map released: 03/12/2025
Last modified: 03/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Inosine 5'-monophosphate dehydrogenase 2 - S160del mutant, bound to GTP, ATP, IMP, and NAD+
Fitted models: 9mub

Deposition Authors: O'Neill AG , Kollman JM

Overexpression of pathogenic human IMPDH2 variant in Xenopus tropicalis disrupts somitogenesis
O'Neill AG , McCartney ME , Wheeler GM , Patel JH , Kollman JM , Wills AE
To Be Published