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EMD-48575
G002-293-0536 Fab in complex with 001428_T278M_L14 SOSIP and RM20A3 Fab
EMD-48575
Single-particle3.2 Å
Deposition: 09/01/2025Map released: 28/05/2025
Last modified: 13/08/2025
Sample Organism:
Homo sapiens,
Macaca mulatta,
Human immunodeficiency virus 1
Sample: G002-293-0536 Fab in complex with 001428_T278M_L14 SOSIP and RM20A3 Fab
Fitted models: 9msd
Deposition Authors: Phulera S
,
Ozorowski G
,
Ward AB
Sample: G002-293-0536 Fab in complex with 001428_T278M_L14 SOSIP and RM20A3 Fab
Fitted models: 9msd
Deposition Authors: Phulera S
,
Ozorowski G
,
Ward AB
Vaccination with mRNA-encoded nanoparticles drives early maturation of HIV bnAb precursors in humans.
Willis JR
,
Prabhakaran M
,
Muthui M
,
Naidoo A
,
Sincomb T
,
Wu W
,
Cottrell CA
,
Landais E
,
deCamp AC
,
Keshavarzi NR
,
Kalyuzhniy O
,
Lee JH
,
Murungi LM,
Ogonda WA,
Yates NL
,
Corcoran MM
,
Phulera S
,
Musando J,
Tsai A,
Lemire G,
Sein Y
,
Muteti M
,
Alamuri P,
Bohl JA,
Holman D
,
Himansu S
,
Leav B,
Reuter C
,
Lin LA
,
Ding B
,
He C,
Straus WL,
MacPhee KJ
,
Regadas I,
Nyabundi DV,
Chirchir R,
Anzala O,
Kimotho JN
,
Kibet C
,
Greene K,
Gao H
,
Beatman E
,
Benson K
,
Laddy D,
Brown DM
,
Bronson R
,
Jean-Baptiste J
,
Gajjala S
,
Rikhtegaran-Tehrani Z,
Benner A
,
Ramaswami M
,
Lu D
,
Alavi N
,
Amirzehni S,
Kubitz M,
Tingle R
,
Georgeson E
,
Phelps N
,
Adachi Y
,
Liguori A
,
Flynn C
,
McKenney K
,
Zhou X
,
Owuor DC,
Owuor SA
,
Kim SY
,
Duff M,
Kim JY
,
Gibson G
,
Baboo S
,
Diedrich J,
Schiffner T
,
Shields M,
Matsoso M
,
Santos J
,
Syvertsen K
,
Kennedy A,
Schroeter M
,
Vekemans J,
Yates 3rd JR
,
Paulson JC
,
Hyrien O
,
McDermott AB
,
Maenetje P
,
Nyombayire J,
Karita E
,
Ingabire R,
Edward V
,
Muturi-Kioi V
,
Maenza J
,
Shapiro AE
,
McElrath MJ
,
Edupuganti S
,
Taylor BS,
Diemert D,
Ozorowski G
,
Koup RA
,
Montefiori D,
Ward AB
,
Karlsson Hedestam GB
,
Tomaras G,
Hunt DJ
,
Muema D
,
Sok D
,
Laufer DS
,
Andrews SF
,
Nduati EW
,
Schief WR
(2025) Science , 389 , eadr8382 - eadr8382
,
Prabhakaran M
,
Muthui M
,
Naidoo A
,
Sincomb T
,
Wu W
,
Cottrell CA
,
Landais E
,
deCamp AC
,
Keshavarzi NR
,
Kalyuzhniy O
,
Lee JH
,
Murungi LM,
Ogonda WA,
Yates NL
,
Corcoran MM
,
Phulera S
,
Musando J,
Tsai A,
Lemire G,
Sein Y
,
Muteti M
,
Alamuri P,
Bohl JA,
Holman D
,
Himansu S
,
Leav B,
Reuter C
,
Lin LA
,
Ding B
,
He C,
Straus WL,
MacPhee KJ
,
Regadas I,
Nyabundi DV,
Chirchir R,
Anzala O,
Kimotho JN
,
Kibet C
,
Greene K,
Gao H
,
Beatman E
,
Benson K
,
Laddy D,
Brown DM
,
Bronson R
,
Jean-Baptiste J
,
Gajjala S
,
Rikhtegaran-Tehrani Z,
Benner A
,
Ramaswami M
,
Lu D
,
Alavi N
,
Amirzehni S,
Kubitz M,
Tingle R
,
Georgeson E
,
Phelps N
,
Adachi Y
,
Liguori A
,
Flynn C
,
McKenney K
,
Zhou X
,
Owuor DC,
Owuor SA
,
Kim SY
,
Duff M,
Kim JY
,
Gibson G
,
Baboo S
,
Diedrich J,
Schiffner T
,
Shields M,
Matsoso M
,
Santos J
,
Syvertsen K
,
Kennedy A,
Schroeter M
,
Vekemans J,
Yates 3rd JR
,
Paulson JC
,
Hyrien O
,
McDermott AB
,
Maenetje P
,
Nyombayire J,
Karita E
,
Ingabire R,
Edward V
,
Muturi-Kioi V
,
Maenza J
,
Shapiro AE
,
McElrath MJ
,
Edupuganti S
,
Taylor BS,
Diemert D,
Ozorowski G
,
Koup RA
,
Montefiori D,
Ward AB
,
Karlsson Hedestam GB
,
Tomaras G,
Hunt DJ
,
Muema D
,
Sok D
,
Laufer DS
,
Andrews SF
,
Nduati EW
,
Schief WR
(2025) Science , 389 , eadr8382 - eadr8382
Grant Support:
- Bill & Melinda Gates Foundation: INV-002916 (United States)
