EMD-48452

Single-particle
5.6 Å
EMD-48452
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Deposition: 25/12/2024
Map released: 28/05/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48452
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9mo9 summary report (pdf.gz) Map and 9mo9 FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-free rotated state (lower strand)

EMD-48452

Single-particle
5.6 Å
EMD-48452
3D View Gallery
Deposition: 25/12/2024
Map released: 28/05/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Native murine cardiac thin filament variant I79N in troponin T at pCa=5.8
Fitted models: 9mo9

Deposition Authors: Risi CM, Galkin VE
The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn.
Risi CM, Landim-Vieira M, Belknap B, Chase PB, Pinto JR, Galkin VE
(2025) J.Mol.Cell.Cardiol. , 204 , 55 - 67
PUBMED: 40412797
DOI: doi:10.1016/j.yjmcc.2025.05.005
ISSN: 1095-8584