EMD-48313

Single-particle
4.3 Å
EMD-48313
3D View Gallery
Deposition: 14/12/2024
Map released: 21/01/2026
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48313
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9mja summary report (pdf.gz) Map and 9mja FULL report (pdf.gz)
EMICSS annotations (xml)

PARP1 ART in complex with HPF1 and EB47

EMD-48313

Single-particle
4.3 Å
EMD-48313
3D View Gallery
Deposition: 14/12/2024
Map released: 21/01/2026
Last modified: 21/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Full-length human PARP1 bound to nicked DNA and in complex with HPF1 and Timeless fragment
Fitted models: 9mja

Deposition Authors: Sverzhinsky A, Pascal JM

Structure and dynamics of PARP1-HPF1 engaging nicked DNA suggests a mechanism for acute production of localized ADP-ribose modifications
Sverzhinsky A, Xue H, Langelier M-F, Del Mundo J, Classen S, Hammel M, Rothenberg E, Pascal JM
To Be Published