EMD-48273

Single-particle
7.0 Å
EMD-48273
3D View Gallery
Deposition: 11/12/2024
Map released: 12/02/2025
Last modified: 12/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48273
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EMICSS annotations (xml)

PI3KC3-C1 bound to RAB1A, VPS34 in active state.

EMD-48273

Single-particle
7.0 Å
EMD-48273
3D View Gallery
Deposition: 11/12/2024
Map released: 12/02/2025
Last modified: 12/02/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Phosphatidylinositol-3 kinase class III complex I bound to RAB1A

Deposition Authors: Cook ASI, Chen M, Hurley JH

Structural pathway for class III PI 3-kinase activation by the myristoylated GTPbinding pseudokinase VPS15
Cook ASI, Chen M, Ngyuen TN, Claveras-Cabezudo A, Khuu G, Rao S, Garcia SN, Yang M, Iavarone AT, Ren X, Lazarou M, Hummer G, Hurley JH
To Be Published
Grant Support: