EMD-48242

Single-particle
3.3 Å
EMD-48242
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Deposition: 10/12/2024
Map released: 17/12/2025
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48242
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Motor domain-Pac1 complex with ADP AAA1 and Apo AAA3 from yeast full-length dynein-1 and Pac1 in 0.1 mM ATP condition

EMD-48242

Single-particle
3.3 Å
EMD-48242
3D View Gallery
Deposition: 10/12/2024
Map released: 17/12/2025
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Saccharomyces cerevisiae
Sample: Motor domain-Pac1 complex with ADP AAA1 and Apo AAA3 from yeast full-length dynein-1 and Pac1 in 0.1 mM ATP condition
Fitted models: 9mfy

Deposition Authors: Geohring IC, Chai P, Iyer BR
A nucleotide code governs Lis1's ability to relieve dynein autoinhibition.
Geohring IC, Chai P, Iyer BR, Ton WD, Yang J, Ide AH, George SC, Bagri JS, Baird SV, Zhang K, Markus SM
(2026) Nat Chem Biol , 22 , 649 - 662
PUBMED: 41571912
DOI: doi:10.1038/s41589-025-02096-8
ISSN: 1552-4469