EMD-48183

Single-particle
3.2 Å
EMD-48183
3D View Gallery
Deposition: 06/12/2024
Map released: 26/11/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48183
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9me4 summary report (pdf.gz) Map and 9me4 FULL report (pdf.gz)
EMICSS annotations (xml)

Antibody fragments from mAb475 and mAb824 bound to the adhesin protein FimH

EMD-48183

Single-particle
3.2 Å
EMD-48183
3D View Gallery
Deposition: 06/12/2024
Map released: 26/11/2025
Last modified: 10/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Escherichia coli, Escherichia coli K-12
Sample: Antibody fragments from mAb475 and mAb824 bound to the E. coli adhesin protein FimH
Fitted models: 9me4

Deposition Authors: Hvorecny KL , Magala P, Klevit RE , Kollman JM
Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference.
Hvorecny KL , Interlandi G, Veth TS , Aprikian P, Manchenko A , Tchesnokova VL, Dickinson MS, Quispe JD, Riley NM , Klevit RE , Magala P, Sokurenko EV, Kollman JM
(2025) Nat Commun , 16 , 10590 - 10590
PUBMED: 41298446
DOI: doi:10.1038/s41467-025-65666-3
ISSN: 2041-1723