EMD-48142

Single-particle
2.61 Å
EMD-48142
3D View Gallery
Deposition: 03/12/2024
Map released: 18/06/2025
Last modified: 07/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48142

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9ekz summary report (pdf.gz) Map-9ekz FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

(+)ML-SI3 bound TRPML2 in an open state

EMD-48142

Single-particle
2.61 Å
EMD-48142
3D View Gallery
Deposition: 03/12/2024
Map released: 18/06/2025
Last modified: 07/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: (+)ML-SI3 bound TRPML2
Fitted models: 9ekz

Deposition Authors: Schmiege P , Li X
TRPML2 in distinct states reveals the activation and modulation principles of the TRPML family.
Schmiege P , Jaslan D , Fine M, Sadanandan NP, Hatton A, Elghobashi-Meinhardt N , Grimm C , Li X
(2025) Nat Commun , 16 , 5325 - 5325
PUBMED: 40527873
DOI: doi:10.1038/s41467-025-60710-8
ISSN: 2041-1723