EMD-48125

Single-particle
8.31 Å
EMD-48125
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Deposition: 02/12/2024
Map released: 22/10/2025
Last modified: 22/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-48125
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Cryo-EM Map of Brucella Abortus Lumazine Synthase (BLS) Engineered with Shiga Toxin I subunit B (Stx1B) Complexed with Equine Polyclonal Fab Fragments (Complex 3)

EMD-48125

Single-particle
8.31 Å
EMD-48125
3D View Gallery
Deposition: 02/12/2024
Map released: 22/10/2025
Last modified: 22/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli O157:H7
Sample: Chimeric BLS-Stx1B protein complexed with polyclonal Fab 3

Deposition Authors: Cristofalo AE, Sharma A, Cerutti ML, Sharma K, Melero R, Zylberman V, Goldbaum FA, Borgnia MJ, Otero LH
Cryo-EM structures of engineered Shiga toxin-based immunogens capable of eliciting neutralizing antibodies with therapeutic potential against hemolytic uremic syndrome.
Cristofalo AE, Sharma A, Cerutti ML, Sharma K, Melero R, Pardo R, Goldbaum FA, Borgnia M, Zylberman V, Otero LH
(2025) Protein Sci , 34 , e70178 - e70178
PUBMED: 40411437
DOI: doi:10.1002/pro.70178
ISSN: 1469-896X
ASTM: PRCIEI