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EMD-47882

Single-particle
3.44 Å
EMD-47882
3D View Gallery
Deposition: 12/11/2024
Map released: 26/03/2025
Last modified: 16/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47882
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9ebn summary report (pdf.gz) Map and 9ebn FULL report (pdf.gz)
EMICSS annotations (xml)

Peptide 1 (GLP-1 (Aib16, ACPC18)) bound to GLP-1R/Gs complex

EMD-47882

Single-particle
3.44 Å
EMD-47882
3D View Gallery
Deposition: 12/11/2024
Map released: 26/03/2025
Last modified: 16/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Hetero 6-mer of GLP-1R, G-alpha-S, G-beta-1, G-gamma-2, nanobody35, and peptide 1 (GLP-1 (Aib16, ACPC18))
Fitted models: 9ebn

Deposition Authors: Cary BP , Hager MV, Mariam Z, Morris RK, Belousoff MJ, Deganutti G , Wootten D, Sexton PM , Gellman SH
Prolonged signaling of backbone-modified glucagon-like peptide- 1 analogues with diverse receptor trafficking.
Cary BP , Hager MV, Mariam Z, Morris RK, Belousoff MJ, Deganutti G , Sexton PM , Wootten D, Gellman SH
(2025) PNAS , 122 , e2407574122 - e2407574122
PUBMED: 40168114
DOI: doi:10.1073/pnas.2407574122
ISSN: 1091-6490
ASTM: PNASA6