EMD-47745
Subtomogram average of capsid (CA) from immature Enveloped Delivery Vehicles (EDVs) containing Cas9
EMD-47745
Subtomogram averaging9.5 Å
Deposition: 07/11/2024Map released: 15/01/2025
Last modified: 22/01/2025
Sample Organism:
lentivirus derived Envelope Delivery Vehicle (EDV)
Sample: lentivirus derived envelope delivery vehicle
Deposition Authors: Peukes J
,
Ngo W
,
Nogales E
,
Doudna J
Sample: lentivirus derived envelope delivery vehicle
Deposition Authors: Peukes J
,
Ngo W
,
Nogales E
,
Doudna J
Mechanism-guided engineering of a minimal biological particle for genome editing.
Ngo W
,
Peukes J
,
Baldwin A,
Xue ZW
,
Hwang S,
Stickels RR
,
Lin Z
,
Satpathy AT,
Wells JA
,
Schekman R
,
Nogales E
,
Doudna JA
(2025) PNAS , 122 , e2413519121 - e2413519121
,
Peukes J
,
Baldwin A,
Xue ZW
,
Hwang S,
Stickels RR
,
Lin Z
,
Satpathy AT,
Wells JA
,
Schekman R
,
Nogales E
,
Doudna JA
(2025) PNAS , 122 , e2413519121 - e2413519121
Grant Support:
- European Molecular Biology Organization (EMBO): ALTF 1031-2021 (European Union)
- Alexander von Humboldt Foundation: (Germany)
- Natural Sciences and Engineering Research Council (NSERC, Canada): PDF-578176-2023 (Canada)
- Howard Hughes Medical Institute (HHMI): (United States)
- Other government: DE-AC52-07NA27344
