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EMD-47732

Helical reconstruction
3.0 Å
EMD-47732
3D View Gallery
Deposition: 06/11/2024
Map released: 12/11/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47732
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9e8v summary report (pdf.gz) Map and 9e8v FULL report (pdf.gz)
EMICSS annotations (xml)

Complex fibril structure of MSA alpha-synuclein with CNS-11g at 4 hours

EMD-47732

Helical reconstruction
3.0 Å
EMD-47732
3D View Gallery
Deposition: 06/11/2024
Map released: 12/11/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Alpha-synuclein with CNS-11g
Fitted models: 9e8v

Deposition Authors: Lu J , Sawaya MR , Ge P , Boyer DR , Eisenberg DS

The small molecule CNS-11g forms amyloid-like fibrils that disassemble pathological alpha-synuclein fibrils
Lu J , Sawaya MR , Cheng XY, Murrali MG , Ge P , Jiang YX , Cascio D , Lutter L , Boyer DR , Williams CK, Shino M, Feigon J, Chaturvedi S, Alexandrova A, Eisenberg DS
To Be Published