Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-47706

Single-particle
3.6 Å
EMD-47706
3D View Gallery
Deposition: 05/11/2024
Map released: 01/10/2025
Last modified: 03/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47706
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9e84 summary report (pdf.gz) Map and 9e84 FULL report (pdf.gz)
EMICSS annotations (xml)

De Novo Mycobacterium tuberculosis transcription initiation promoter complex with 6-mer RNA and disordered Sigma-A region 4 domain (RNA Polymerase with Sigma-A, CarD, and RbpA)

EMD-47706

Single-particle
3.6 Å
EMD-47706
3D View Gallery
Deposition: 05/11/2024
Map released: 01/10/2025
Last modified: 03/12/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mycobacterium tuberculosis, synthetic construct
Sample: Off-pathway Mycobacterium tuberculosis transcription initiation promoter complex (RNA Polymerase with Sigma-A, CarD, and RbpA)
Fitted models: 9e84

Deposition Authors: Brewer JJ, Campbell EA , Darst SA
Structural Insights into De Novo Promoter Escape by Mycobacterium tuberculosis RNA Polymerase.
Brewer J , Delbeau M, Zoullas WB , Darst SA , Campbell EA
(2025) Nat Commun , 16 , 9990 - 9990
PUBMED: 41233305
DOI: doi:10.1038/s41467-025-64941-7
ISSN: 2041-1723