EMD-47577

Single-particle
15.0 Å
EMD-47577
3D View Gallery
Deposition: 30/10/2024
Map released: 18/12/2024
Last modified: 18/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47577
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Negative stain EM map of polyclonal serum from mouse immunized with MERS-CoV NTD-I53-50 in complex with MERS S-2P

EMD-47577

Single-particle
15.0 Å
EMD-47577
3D View Gallery
Deposition: 30/10/2024
Map released: 18/12/2024
Last modified: 18/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Immune complex of prefusion MERS-CoV spike glycoprotein stabilized with 2P mutations with polyclonal Fabs from mice immunized with MERS-CoV NTD-I53-50.

Deposition Authors: Chao CW , King NP
Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV.
Chao CW , Sprouse KR, Miranda MC, Catanzaro NJ, Hubbard ML, Addetia A, Stewart C, Brown JT, Dosey A, Valdez A, Ravichandran R, Hendricks GG , Ahlrichs M, Dobbins C, Hand A, McGowan J, Simmons B, Treichel C, Willoughby I, Walls AC, McGuire AT, Leaf EM, Baric RS, Schafer A, Veesler D, King NP
(2024) Cell Rep , 43 , 115036 - 115036
PUBMED: 39644492
DOI: doi:10.1016/j.celrep.2024.115036
ISSN: 2211-1247